We searched high and low for the highest quality CBD and we found it at Pinnacle Distribution. This is the high quality CBD made from plant extract not crystal which has the highest medicinal qualities. CBD helps with everything from muscle and joint pain to insomnia and anxiety. You can either drip this like you would e-liquid or put the drops directly under your tongue. Each bottle contains 300mg of pure CBD in a 15ml bottle. This product is legal in all 50 states without a prescription. George and I both use this product and we love it. We both sleep better and it has really helped us with the aches and pains we both have from car accidents.
Here is some science information on this plant based CBD.
Crystal VS Plant based CBD and the
Most animal studies with cannabidiol utilize synthetic, single-molecule CBD produced by biochemical
laboratories for research purposes. In contrast, whole plant extractions typically include CBD, THC,
and more than 400 trace compounds. Many of these compounds interact synergistically to create
what scientists refer to as an “entourage effect” that magnifies the therapeutic benefits of the plant’s
individual components—so that the medicinal impact of the whole plant is greater than the sum of its
It is important to consider the entourage effect (or lack thereof) when extrapolating data based on
animal studies: 100 milligrams of synthetic single-molecule CBD is not equivalent to 100 milligrams
of a CBD-rich whole plant cannabis extract.
“Cannabis is inherently poly-pharmaceutical,” Dr. John McPartland notes, “and synergy arises from
interactions between its multiple components.”
Consider the role of terpenes, for example. Terpenes are volatile aromatic molecules that evaporate
easily and readily announce themselves to the nose. Various researchers have emphasized the
pharmacological importance of terpenes, or terpenoids, which form the basis of aromatherapy, a
popular holistic healing modality. Marijuana’s compelling fragrance and particular psychoactive flavor
are determined by the predominate terpenes in a strain.
Around 200 terpenes have been found in cannabis, but only a few of these odiferous oily substances
appear in amounts substantial enough to be noteworthy, or nose worthy, as it were. Among them are
monoterpenes, diterpenes, and sesquiterpenes, which are characterized by the number of repeating
units of a 5-carbon molecule called isoprene, the structural hallmark of all terpenoid compounds. The
terpenes in marijuana have given the plant an enduring, evolutionary advantage. Pungent terpenoid
oils repel insects and animal grazers; others
Terpenes, it turns out, are healthy for people as well as plants. A September 2011 report by Dr.
Ethan Russo in the British Journal of Pharmacology discussed the wide-ranging therapeutic
attributes of terpenoids, which are typically lacking in “CBD-only” products.
Beta-caryophyllene, for example, is a sesquiterpene found in the essential oil of black pepper,
oregano, and other edible herbs, as well as in various cannabis strains and in many green, leafy
vegetables. It is gastro-protective, good for treating certain ulcers, and offers great promise as a
therapeutic compound for inflammatory conditions and auto-immune disorders because it binds
directly to the peripheral cannabinoid receptor known as “CB2.”
In 2008, the Swiss scientist Jürg Gertsch documented beta-caryophyllene’s binding affinity for the
CB2 receptor and described it as “a dietary cannabinoid.” It is the only terpenoid known to directly
activate a cannabinoid receptor. And it’s one of the reasons why green, leafy vegetables are so
healthy to eat.
Terpenoids and cannabinoids both increase blood flow, enhance cortical activity, and kill respiratory
pathogens, including MRSA, the antibiotic-resistant bacteria that in recent years has claimed the
lives of tens of thousands of Americans. Dr. Russo’s article reports that cannabinoid-terpenoid
interactions “could produce synergy with respect to treatment of pain, inflammation, depression,
anxiety, addiction, epilepsy, cancer, fungal and bacterial infections.”
Marijuana’s bouquet of terpenes—that “riot of perfumes,” as the poet (and hashish-eater) Arthur
Rimbaud once said—plays another important role. Terpenes and CBD buffer THC’s tricky
psychoactivity. Cannabinoid-terpenoid interactions amplify the beneficial effects of cannabis while
mitigating THC-induced anxiety.
The terpenoid profile can vary considerably from strain to strain. Patients who abandon a suitable
strain for one with higher THC and/or CBD content may not get more relief if the terpenoid profile is
significantly different. The nose knows: Choose a cannabis strain that smells good to you.